BOC-D-PROLINE METHYL ESTER
Boc-D-Proline methyl ester
CAS: 73323-65-6
Molecular Formula: C11H19NO4
BOC-D-PROLINE METHYL ESTER - Names and Identifiers
| Name | Boc-D-Proline methyl ester |
| Synonyms | BOC-D-PRO-OME BOC-D-PYRD(2)-OME BOC-D-PROLINE METHYL ESTER Boc-D-Proline methyl ester Boc-D-Proline-methyl ester BOC-D-PROLINE METHYLESTER LIQUID N-tert-Butoxycarbonyl-D-Proline methyl ester N-ALPHA-T-BUTOXYCARBONYL-D-PROLINE METHYL ESTER R-1-BOC-PYRROLIDINE-2-CARBOXYLIC ACID METHYL ESTER 1-tert-butyl 2-methyl (2R)-pyrrolidine-1,2-dicarboxylate N-ALPHA-T-BUTOXYCARBONYL-D-PYRROLIDINE-2-CARBOXYLIC ACID METHYL ESTER |
| CAS | 73323-65-6 |
| EINECS | 233-720-0 |
| InChI | InChI=1/C11H19NO4/c1-11(2,3)16-10(14)12-7-5-6-8(12)9(13)15-4/h8H,5-7H2,1-4H3/t8-/m1/s1 |
BOC-D-PROLINE METHYL ESTER - Physico-chemical Properties
| Molecular Formula | C11H19NO4 |
| Molar Mass | 229.27 |
| Density | 1.120±0.06 g/cm3(Predicted) |
| Boling Point | 288.6±33.0 °C(Predicted) |
| Flash Point | 128.3°C |
| Solubility | Soluble in DMSO. |
| Vapor Presure | 0.00232mmHg at 25°C |
| Appearance | White to bright yellow crystals |
| Color | Clear Colourless |
| pKa | -3.35±0.40(Predicted) |
| Storage Condition | Sealed in dry,2-8°C |
| Refractive Index | 1.4510-1.4550 |
| MDL | MFCD00190828 |
BOC-D-PROLINE METHYL ESTER - Risk and Safety
| Hazard Class | IRRITANT |
BOC-D-PROLINE METHYL ESTER - Introduction
Boc-D-Proline methyl ester(Boc-D-Proline methyl ester) is a chemical reagent and a derivative of a protected amino acid. It has the following properties:
1. Appearance: colorless or yellowish solid;
2. molecular formula: C13H20N2O4;
3. Molecular weight: 268.31g/mol;
4. Melting point: 78-80 degrees Celsius.
Boc-D-Proline methyl ester is mainly used for peptide synthesis reactions in organic synthesis. It is commonly used as a derivative of proline for the N protecting group in solid phase synthesis. Proline is a common chiral amino acid frequently used in pharmaceutical research and fine chemical synthesis.
The method for preparing Boc-D-Proline methyl ester is usually by obtaining D-proline, and then reacting with methanol under acidic conditions to generate the corresponding methyl esterification product. Next, the amino group is protected using a Boc protecting group to generate the Boc-D-Proline methyl ester.
Regarding safety information, Boc-D-Proline methyl ester is a chemical substance, the following safety precautions should be paid attention to when using it:
1. pay attention to protection: use should wear chemical safety glasses, protective gloves and laboratory coats and other personal protective equipment;
2. avoid inhalation: avoid inhaling its dust or gas;
3. Avoid contact with the skin: avoid prolonged contact with the skin, such as contact should be immediately washed with soap and water;
4. storage conditions: stored in a dry, low temperature, away from the fire and oxidant.
Before use, it is recommended to refer to the relevant chemical substance safety data sheet (MSDS) for more detailed safety information and use it under appropriate experimental conditions.
1. Appearance: colorless or yellowish solid;
2. molecular formula: C13H20N2O4;
3. Molecular weight: 268.31g/mol;
4. Melting point: 78-80 degrees Celsius.
Boc-D-Proline methyl ester is mainly used for peptide synthesis reactions in organic synthesis. It is commonly used as a derivative of proline for the N protecting group in solid phase synthesis. Proline is a common chiral amino acid frequently used in pharmaceutical research and fine chemical synthesis.
The method for preparing Boc-D-Proline methyl ester is usually by obtaining D-proline, and then reacting with methanol under acidic conditions to generate the corresponding methyl esterification product. Next, the amino group is protected using a Boc protecting group to generate the Boc-D-Proline methyl ester.
Regarding safety information, Boc-D-Proline methyl ester is a chemical substance, the following safety precautions should be paid attention to when using it:
1. pay attention to protection: use should wear chemical safety glasses, protective gloves and laboratory coats and other personal protective equipment;
2. avoid inhalation: avoid inhaling its dust or gas;
3. Avoid contact with the skin: avoid prolonged contact with the skin, such as contact should be immediately washed with soap and water;
4. storage conditions: stored in a dry, low temperature, away from the fire and oxidant.
Before use, it is recommended to refer to the relevant chemical substance safety data sheet (MSDS) for more detailed safety information and use it under appropriate experimental conditions.
Last Update：2024-04-09 20:02:46
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CAS: 73323-65-6
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